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A larger randomized, placebo-controlled intervention trial (the SELECT study) in more than 35,000 middle-aged and selenium-replete men, randomized to receive selenium (in the form of selenomethionine, 200 g/day) and/or vitamin E supplementation, was halted because of concerns regarding an increased risk of type 2 diabetes mellitus with selenium and increased risk of prostate cancer with vitamin E (84, 85)

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The results of this study illustrated that supplementing Spirulina to the broilers diet can successfully mitigate the adverse effect of OTA toxicosis on broiler pathological changes of lymphoid organs such as the bursa and thymus