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In bleeding patients, hemoglobin levels may not reflect tissue oxygenation as fluid shifts occur in parallel to transfusion

Factors contributing to the suboptimal performance of drugs include the selection of drug targets, the use of biomarkers and animal models in experimental designs, and other issues such as late treatment initiation, dose-dependent side effects, challenges in BBB permeability, and the heterogeneous presentation of patients

Report depth: A clinical lab returns a binary variant result

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