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Studies in animals with medically induced kidney injury found that hydrangea extract significantly reduced BUN levels ( One of these studies also observed less kidney damage in mice treated with the extract, compared with a control group ( Another study similarly found that skimmin, an active molecule found in hydrangea extract, reduced BUN, blood creatinine, and urinary albumin excretion (UAE) in mice with kidney inflammation

Bezafibrate also attenuated the ascites-mediated protection against ferroptosis across multiple OVCA cell lines, including TYKNU, TOV21G, and TOV112D (Supplementary Fig

In spite of the fact that animal model results are reliable, there is no extensive clinical evidence available

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