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This initial phosphorylation cascade leads to autophosphorylation of the carboxy-terminal bidentate substrate-binding site (Tyr1349 and Tyr1356) of the c-Met and these residues have been shown as docking sites for downstream signaling molecules [52]

It helps in improving conditions caused due to low levels of vitamin K in the body

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For mKate reporter construction, the mKate2 gene was amplified from pRN10 (Addgene, plasmid 84454) 69 using a specific primer pair (Supplementary Table 3) and Q5 High-Fidelity DNA Polymerase (New England Biolabs)