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Studies of the few surviving KO mice (less than 5%), however, show continually retarded bone growth (27,28), suggesting that IGF-I signaling is also essential for skeletal development during post-natal growth

Gibellini, T.K

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HyPer7 has been previously shown to be highly selective for H 2 O 2 and sensitive enough to detect gradients of mitochondrial ROS in living organisms 11,12,31