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[25], with hypertrophy defined as above 115 g/m 2 for men and 95 g/m 2 [24] and an enlarged left atrium defined as above 34 mL/m 2

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"But IgG antibodies never cross the cell layers and they can never make it inside the cysts." This limitation is crucial, he added, because the interior of each cyst -- essentially a sealed chamber lined with epithelial cells -- is the location where disease-driving activity occurs

The Interpretive Limitation Finally, the deepest limitation is interpretive: it is tempting to read the solid reconstitution arithmetic as if it validated the doses it computes