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610 In addition, DR-AB enhances the formation of the cell membrane NKA-1 /SLC7A11 complex and inhibits SLC7A11-dependent ferroptosis

The nonenzymatic antioxidants ascorbate (AsA) and glutathione (GSH), their respective oxidized formsdehydroascorbate (DHA) and glutathione disulphide (GSSG) and the enzymes that continuously recycle them constitute the major ROS scavenging system in plantsthe ascorbateglutathione cycle

Genetic polymorphism in the genes ABCB1 , ABCC1 , ACTG1 , CAPG , MAP4 , SLC5A7 , TTPA and TUBB1 could modulate the risk of developing neuropathy in children following vincristine treatment (Wright et al., 2019)

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