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Furthermore, it enhances the livers own antioxidant defenses, such as glutathione, a crucial detoxifying agent, thereby strengthening the organs resilience against various stressors

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This contrasts with observations from various other tissues and cells exposed to high glucose levels in vitro, typically within the 20 mM to 30 mM range, where chronic exposure (e.g., in podocytes, endothelial cells, myotubes, epithelial cells, pancreatic cells, and aortic tissues) often resulted in basal respiration rates that either remained unchanged or were reduced (Audzeyenka et al