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Description

(2010) Journal of Biological Chemistry

While traditional synthetic nanomaterials demonstrate strong therapeutic efficacy, their persistence and toxicity raise significant environmental concerns

Recent clinical research has increasingly pointed to a profound cellular energy crisis driven by severe oxidative stress and the depletion of a critical molecule called glutathione

Development and testing of advanced delivery strategies, such as nanoformulations and prodrugs, are needed to overcome bioavailability challenges and improve central nervous system penetration and target engagement