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Researcher Loren Pickart, PhD, who first isolated GHK from human plasma, described it as having a "profound effect on the reset of human genes toward a more youthful state." More recent genomic analyses confirm that GHK-Cu shifts gene expression patterns in aging tissue toward patterns characteristic of much younger tissue effectively acting as a biological reset at the cellular level

This study observed increased MDA and decreased antioxidants such as SOD, CAT, GPX and GSH in ISO-treated rat heart tissues

For research context, see our dedicated article on GHK-Cu and hair loss research and our overview of peptides for hair growth research

Chemically, Ipamorelin is a pentapeptide (five amino acids long) that mimics the action of ghrelin , the bodys hunger hormone, by binding to the GHS-R1a receptor in the pituitary gland