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10.1111/j.1440-1746.2006.04644.x J Gastroenterol Hepatol

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Conclusion Despite significant advancements in understanding GBM pathogenesis, effective treatments remain elusive because of tumor heterogeneity, adaptability, and complex interactions with the TME

*Correspondence: Yongzhi Shan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers