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10.3389/fpls.2014.00487 125 SaitoT.ChikuT.OkaM.Wada-KakudaS.NobuharaM.ObaT.et al (2021)

Diphthamide is an evolutionarily conserved post-translational modification that occurs at a single histidine residue of translation elongation factor 2 (EF-2), which is needed for accurate protein translation by preventing -1 frameshift slippage during translation (Liu et al, 2012)