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Recent advances in clinical trials of glutamine metabolism inhibitors In the landscape of oncological research, the inhibition of glutamine metabolism has emerged from preclinical studies as a compelling avenue for therapeutic intervention, sparking fervent interest in its clinical application

Small-molecule allosteric inhibitors of GPX4

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248 Additionally, excessive copper increases cellular autophagy levels through the Cu-mTORC1-TFEB signaling pathway, where TFEB acts as a regulator of lysosomal biogenesis