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4 Results of a study of dogs treated with trilostane found that only 15% of dogs experienced an episode of Cushing's syndrome during the first 2 years of treatment, and 25% experienced an episode over a 4-year treatment period.5 Because of the reversible action of the drug, many dogs that experience a hypoadrenocortical crisis will respond to supportive treatment and temporary discontinuation of trilostane

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Greenfield JM, Shah SJ and Levine LA: Verapamil versus saline in electromotive drug administration for Peyronie's disease: a double-blind, placebo controlled trial