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further demonstrated that SLC25A39 and SLC25A40 cooperatively regulate mitochondrial GSH transport, with SLC25A40 expression influenced by Toll-like receptor 4 (TLR4) and receptor for advanced glycation end products (RAGE) signaling pathways 18

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1C, D), supporting prior data showing that activation of this pathway results in resistance to CDK4/6 inhibitors 18,19,22,23,24

Nanomedicine-induced programmed cell death in cancer therapy: mechanisms and perspectives