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and Novak, N., 2007

Further direct evidence of the involvement of TET enzymes in DNA repair come from studies in ESCs, where genotoxic insults such as aphidicolin treatment to induce double strand breaks (DSBs) were shown to induce 5hmC, but not 5mC, foci that co-localized with H2AX marks, and the repair proteins 53BP1 and RAD51 (Kafer et al., 2016)

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