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10.1056/NEJMra031573 106 PipernoA.PelucchiS.MarianiR

This is achieved by providing a GSH formulation which ensures delivery of adequate dose of pharmaceutically stabilized, reduced GSH, with rapid dissolution before the duodenum

27,28 Moreover, in some HCC patients treated with sorafenib, concentration of serum oxidative stress response markers was associated with progression-free survival, suggesting that sorafenib-induced ferroptosis plays an important role in patient survival