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Microbial diversity is fundamental to maintaining gut ecosystem homeostasis and overall host health, with its abundance and stability directly shaping the adaptability of the intestinal microecosystem and host physiological function

We further point out that there are there few patients in this study ( n = 7) who were on insulin, hence it is unclear if the observations described here extend to those in whom insulin insufficiency is severe

doi: 10.1038/s41598-020-67383-x 77

T-REX coupled with co-immunoprecipitation assays revealed that NCBP1-HNEylation caused no perturbation of the association between NCBP1 and ALYREF, PHAX or PRPF4 (Supplementary Fig