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Beyond the temperature-cycling concern (refrigerator doors experience wider temperature swings than interior shelves), the door is exposed to room lighting every time the refrigerator is opened

Endocrinology 147 , 38 (2006)

MRI scans further showed progressive degeneration of the puncture-only IVDs with the lowest gray levels 3 months postsurgery, and these IVDs exhibited the worst degenerative degree 17,18 (Fig