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this enhances the elaboration of proinflammatory cytokines and enzymes for ECM degradation and leads to cartilage damage (Han et al., 2025)

B12 has been shown to promote recovery of nerve tissue after traumatic brain injury (TBI) , and to stabilize and reduce the rate of nerve cell death

The serum changes of 6 metabolites involved in glucose metabolism, including increased glycerol-3-phosphate, lactate, citrate, and decreased pyruvate, 2-oxoglutarate, 2-hydroxyglutaric acid (2-HG), have independent prognostic values in AML patients, in which poor prognosis was linked to accelerated glycolysis and activation of the TCA cycle (132)

Gazzin, S