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Yes, some medicines like metformin, proton pump inhibitors , and antibiotics can block B12 absorption

1998 Nov;139(5):552-61

New York, London, Academic Press, p 597

Table 3 Sleep and Recovery Optimization Therapeutic Peptides and Molecular Pathways Epithalon Epithalon is a synthetic tetrapeptide derived from the pineal gland peptide, epithalamin