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This work was funded by the Deutsche Forschungsgemeinschaft (DFG) project SFB 779, TP B6, the DFG grant LE 1020/2-1, project SFB 779, TP B6, the DFG grant LE 1020/2-1, SFB 779, TP B6, the EU Joint ProgrammeNeurodegenerative Disease Research (JPND) project CIRCPROT (jointly funded by BMBF and European Unions Horizon 2020 research and innovation program (No 643417)), the Carl-Zeiss Stiftung (0563-2.8/515/2 and TelMa) and by the Ministerium fr Wissenschaft, Weiterbildung und Kultur (52 171/40)

specificity of 0.6 and sensitivity of 0.63 were calculated, with NPV of 0.82 and PPV of 0.63

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