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doi: 10.1126/science.277.5327.831

By regulating your body's insulin response, dihydroberberine can help reduce cravings and promote fat loss, making it an ideal supplement for weight management

Disruption of the tight endothelial junction can be achieved via the use of a hyperosmotic agent to produce osmotic disruption or use of a vasoactive compound, bradykinin analogs, or other molecules [3]