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Nrf2 translocates to the nucleus and interacts with the antioxidant response element (ARE) of target genes, resulting in expression of antioxidant genes, which induces an antioxidant response shown to be beneficial for several human conditions 48

Interaction of the apo form of PtGSTU19 and 20 with a set of different classes of chemical compounds including coumarins, flavonoids, terpenes, peroxides, and GST substrates have been screened using thermal shift assay (TSA) (Supplementary Table S2)

H2Se can also form, by cysteine synthase, SeCyS, which is cotranslationally inserted into selenoproteins, while it can also synthesize selenophosphate, which is the link to selenoprotein synthesis by selenophosphate synthetase ( Fig