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Vairetti, M., Di Pasqua, L

599 Additionally, Ndfip1 prevents increased expression of ACSL4, significantly improves motor dysfunction, and antagonizes the loss of dopaminergic neurons by inhibiting ferroptosis, 599 indicating that Ndfip1 may be a promising target for iron-related diseases, including PD

Conclusion: Grx2s anti-apoptotic and cytoprotective roles may make it a potential drug target to treat oxidative stress-induced diseases Despite being overlooked, research throughout the years has portrayed Grx2 as a capable and robust antioxidant enzyme through direct detoxification of free radicals, cytoprotection, and anti-apoptotic abilities [5, 23]

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