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10.1378/chest.09-1103 [DOI] [PubMed] [Google Scholar] 48.Keown K, Reid A, Moore JE, Taggart CC, Downey DG

The review authors concluded that key questions around dosing, safety, and clinical outcomes remain unanswered

Altered IgG subtype distribution and the resulting increase in IFN- production are observed in both patients with CGD and a CGD mouse model (29), indicating a possible feedback loop involving IFN-, IgG, FcRs, and NOX2