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Description

Hedychium flavum flower essential oil: chemical composition, anti-inflammatory activities and related mechanisms in vitro and in vivo

Moreover, sporadic and temporally disjointed inflammation can cumulatively exacerbate harm to HSC function, leading to a series of aging-related changes at both the molecular and cellular levels in HSCs 25

At both cellular and organismal levels, UVB exposure enhances the expression of DNMTs, including DNMT1/2/3, and reduces the expression of TETs, including TET1/2/3, leading to hypermethylation of COL4A1 promoter CpG islands and subsequent inhibition of COL4A1 expression (285)