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In addition to S586A, S586G and S586T retained more than 10% activity toward tyrosine, whereas the other mutants showed less than 5% or undetectable activity toward tyrosine or DOPA (Fig

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doi: 10.1007/s10637-013-0032-y 122 KimSTLeeJLeeSJParkSHJungSHParkYSet al

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