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[2] However, as the fifth season's production period entered its final months, rumors began to circulate especially among the production crew members in Vancouver, British Columbia, Canada about the future of the series, particularly concerning whether the show would be moving to Los Angeles, California for the sixth season and whether the new recurring character of Jeffrey Spender was planned (in case David Duchovny cut back his commitment to the series) to become a replacement for Duchovny's character of Fox Mulder either as a part-time or full-fledged substitute

Finally, this study introduces a new measure of exposure to vaping, pack-equivalent years, which is based conceptually on cigarette pack equivalent measures that have been used in respiratory and health effects study of cigarettes for decades

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