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Here's what sits alongside your point: the math explains why things are the way they are, but most people hearing "no FDA approval" instantly think "not safe." The evidence exists

It can effectively scavenge excessive reactive oxygen free radicals in the body, protect the normal structure and function of cells and mitochondria, and prevent the occurrence of lipid peroxidation, thus playing a role in preventing cognitive dysfunction in diabetes (113)

Elevated cyclic AMP can activate downstream signaling intermediates including protein kinase A and related phosphorylation cascades that regulate gene transcription and cellular metabolic responses