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It enhances anti-inflammatory/antibacterial capacity in IPECs and upregulates Claudin-1, EGFR, and IL-10 gene expression ( CB s anti-inflammatory effect exhibits gender heterogeneity in high-fat diet (HFD)-induced Fischer-344 rats ( 3.1.3 Regulate innate immune cell function Besides butyrate-mediated pathways, Clostridium ( FP , CB ) and their derivatives (extracellular matrix [EPM], EVs) directly regulate innate immune cells ( in vitro experiments have clarified the cell type-specific regulatory mechanisms