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[DOI] [PMC free article] [PubMed] [Google Scholar] 121

Through the secretion of these cytokines, Th1 cells in ARDS may be involved in tissue destruction

The rest of the TmGst encoding genes (twelve TmGsts) were downregulated in the yeast phase (Fig

The reduced lysosome function appears multifactorial but includes direct and indirect inhibition of lysosomal acid lipase, the enzyme responsible for hydrolysis of cholesteryl esters in lysosomes, and a reduced capacity for transferring cholesterol from lysosomes (159-162)