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Figueira, A

Severe photo-aging causes extensive profound remodelling of the elastic fibres

found that PF can reduce the release of pro-inflammatory cytokines by regulating TLR4/NF-B/NLRP3 signaling, thus reducing the damage of cytokines to neurons and reversing LPS-induced depression-like behavior in mice ( 6 IU/kg, as modeled by depression-inducing mice