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Japan brand Masshiro introduces glutathione in different forms for Asian consumers MANILA, Philippines Originating from Japan, Masshiro Glutathione uses only raw materials sourced from Asia to cater specifically to Asian consumers and focus on regional efficacy

AX and MZ collected and analyzed the data needed in the article

The silencing of the pi class of GST (GSTP) that displayed the most characteristic expression profile in 13 kinds of cancer cell lines has shown significant impairment in the growth of cancer cells due to oxidative stress caused by excess ROS accumulation

The resulting decrease in the -KG/succinate ratio inhibits the activity of -KG-dependent dioxygenases, leading to a reduction in 5-hydroxymethylcytosine (5hmC) level, epigenetic dysregulation, and ultimately driving tumor cell dedifferentiation and enhanced adaptability [150]