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Although the precise molecular regulatory mechanisms remain to be fully elucidated, these findings highlight the multifaceted therapeutic effects of CNP-miR146a in diabetic wound healing ( Similarly, CS-TA@CeO 2 cryogels, integrating CeO 2 microcubes with chitosan and tannic acid (TA), provide antioxidant and antibacterial functions while supporting fibroblast proliferation and ECM deposition, resulting in enhanced angiogenesis and tissue regeneration in infected full-thickness wound models (Teng et al., 2022)

These small-molecule antagonists block the interaction of GPER with ligands by binding to GPER, thereby inhibiting its signal transduction