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DrMR: Now, a question on that specifically

The duration of treatment ranged from 2 to 6 months

For example, different time and sonication amplitudes must be studied to obtain a final formulation with the desirable CQAs

Predictions of tissue concentrations of inorganic arsenic and its metabolites may be obtained by using physiologically based pharmacokinetic models, although human data to parameterize such models is limited (El-Masri and Kenyon 2008)