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Nanoencapsulation can enhance the stability and circulation of nanoparticles by protecting them from immune recognition and clearance (Perciani et al., 2021)

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With that regulatory brake reduced, IGF-1 LR3 interacts with IGF-1 receptors more directly and for a longer duration, which is why research protocols report a half-life of roughly 2030 hours, compared to native IGF-1s 1215 hours

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Climacteric 23 , 532538 (2020)

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