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Abstract A woman in her 50 s with KleineLevin syndrome (KLS) was referred to our sleep clinic for recurrent episodes of sleep hypersomnia lasting for two to 3 days, despite attempts to remain awake

Neuroimaging studies, including positron emission tomography (PET) and magnetic resonance imaging (MRI), have consistently demonstrated widespread abnormalities in brain regions involved in cognitive control, emotional regulation, and motor function

MiR-146a relieves kidney injury in mice with systemic lupus erythematosus through regulating NF-B pathway

This was claimed to be associated with the enhancement of antioxidant defense in the liver ( Hyperhomocysteinemia is known to induce ER stress, which can activate sterol regulatory element-binding proteins (SREBPs) and upregulate enzymes in lipid synthesis, contributing to triglycerides and cholesterol accumulation and also induces apoptosis ( 4.3.2 Non-alcoholic liver disease In an early pilot study, the non-alcoholic steatohepatitis (NASH) patients who received betaine anhydrous oral solution at a dose of 20 g/day for 1 year resulted in a significant improvement in liver biochemistry and histology