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This could introduce challenges for patients with lifelong anticoagulation needs, such as those with heart failure and atrial fibrillation (Yasueda et al., 2016) and could interact with antihypertensive drugs to cause an excessive drop in blood pressure, necessitating careful monitoring and dose adjustments (Zhao et al., 2022)

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Furthermore, immune dysfunction leads to altered balance within the immune pathways resulting in excess inflammation

In HFD-fed fish, a significant consequence was the downregulation of cpt-1 , acox-1 , and ppar , leading to reduced -oxidation [47]