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For example, 6-O-glycosylated betacyanins showed more powerful activity than 5-O-glycosylated betacyanins

In contrast, mice administered with C34 or C37 demonstrated a 100% survival rate and minimal signs of body weight change or footpad swelling (Fig

Organic acids (e.g., D-(-)-quinic acid) were particularly elevated in the Ca400 and Ca800 treatments

LXR agonists, such as RGX-104 and GW3965, reduce MDSC levels by activating the LXR/ApoE axis and reversing cholesterol transport, thereby improving the anti-tumor response of T cells in preclinical and clinical settings (NCT02922764) in various treatment-refractory tumors, resensitizing patients to anti-PD1 therapy (97)