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To better understand TCM concepts, we have also classified the indicators from the following literature into two categories: Pi deficiency and Dampness excess (Table 5)

Hypoxic conditions result in a more aggressive phenotype of cancer cells, likely due to hypoxia-induced changes in gene expression and subsequent proteomic alterations [47]

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Although that trial did not reverse pre-neoplastic changes, the reduction in cell proliferation supports further investigation of SFN for lung cancer chemoprevention (129)