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Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons

In a murine model of B16F10 melanoma expressing both VEGF-C and chicken ovalbumin (OVA), overexpression of VEGF-C in cancer cells promotes lymphangiogenesis in both primary tumors and TDLNs, leads to CD8+ T cell immune tolerance via LEC cross-presentation ( Figure 1 ), protects tumors against preexisting anti-cancer immunity, and promotes the local elimination of OVA-specific CD8+ T cells (93)

Glutathione-s-transferases are a group of ubiquitous detoxifying enzymes, which are present in all aerobic eukaryotes, which protect cells from the toxic insults by deactivating hydrophobic cytotoxic, genotoxic compounds and reactive oxygen species [75]

Lipo-Stat-Plus MIC with B6 and B12