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Both peptides have been individually evaluated for their potential to influence cellular signalling, inflammation modulation, and regenerative mechanisms in preclinical research

High-dose intraperitoneal N-acetylcysteine (800 mg/kg) induced acute liver, kidney, and spleen damage in mice, leading to mortality

Although subgroup analyses found significant heterogeneity regardless of assay type, literature suggests that different assays have specific characteristics and potential pitfalls [82]

Acknowledgements : We would like to thank Dr Jeffrey Aronson for his helpful comments and Dr Kilin for kindly granting us permission to re-produce his diagram in Figure 1