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J Gerontol Ser A Biol Sci Med Sci

All above samples were diluted (1:1) with 20% ACN/0.1% FA, containing 100 nM of deuterated internal standards and analysed by LC-MS/MS

Due to the lack of an early detection method and effective therapeutics, diagnosis generally occurs at an advanced stage, when patients already have locoregional extensions or metastases that render surgical resection ineffective [4]

Limosilactobacillus reuteri further promotes CD206+ anti-inflammatory macrophages and robust IL-10 production via activation of the TLR1/2STAT3 axis ( Lactobacillus acidophilus inhibits proinflammatory macrophage polarization by upregulating RapGAP ( Akkermansia muciniphila enhances retinoic acid synthesis in dendritic cells, thereby inducing type 3 innate lymphoid cells (ILC3s) to secrete IL-22, a cytokine critical for mucosal repair (Liu H