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Description

Glucagon-like peptide-1 receptor (GLP1R) enhances insulin secretion primarily through cAMP-dependent pathways, promoting insulin exocytosis

19 Monoallelic inactivation of Cx3cr1 is sufficient to significantly reduce the growth of OPG, 19 but the use of available small molecule inhibitors against CX3CR1 has so far not been reported

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doi: 10.3389/fphar.2026.1798309 Received 28 January 2026 Revised 27 February 2026 Accepted 28 February 2026 Published 26 March 2026 Volume 17 - 2026 Edited by Marcos Roberto De Oliveira, Federal University of Rio Grande do Sul, Brazil Reviewed by Maria Jos De Rosa, CONICET Baha Blanca, Argentina Shubham Teli, BVVS Hanagal Shri Kumareshwar College of Pharmacy, India Updates Copyright 2026 Juthi, Ansari, Ahmed, Khan, Seidel, Kumar, Kumari, McKillop, Abdel-Wahab and Flatt