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The gutimmunebrain axis in neurodegenerative disorders Compared with healthy individuals, AD patients have a reduced richness in the gut microbiota composition, with lower Firmicutes and higher Bacteroidetes [327]

Biological activity duration: Despite the short plasma half-life, downstream effects on telomerase expression and pineal regulation persist substantially longer (days to weeks) consistent with Epithalon acting as a signaling molecule triggering longer-lived transcriptional changes rather than direct dose-response activity

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These temporary disturbances generate hydrophilic microchannels, enhancing the penetration of liposomal vesicles and allowing the release of contained pharmaceuticals