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Collectively, GGCT emerges as a pivotal metabolic orchestrator in HCC and PCa, functioning as a bidirectional switch that diverts Gln toward GSH biosynthesis for redox defense while enhancing Glc-fueled TCA anaplerosis to sustain cell proliferation

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A more detailed assessment score than NDS is the Neuropathy Impairment Score (NIS), which evaluates: muscle strengthtested in eight muscle groups through flexion and extension, scored from 0 to 4, where 0 is normal and 4 indicates no activity and sensitivity and reflexesincludes vibration, touch, sharp stimulus and position sense