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Spain R, et al

Grade II HE is more readily discriminated using disorientation and asterixis as markers, which has led to a proposal by the International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) to term HE Grade II as Overt HE (OHE), whereas Grade 1 and mHE may be classed as Covert HE (CHE) [7]