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Subjects aged 18-75 years, smoking 10 or more cigarettes per day were randomized 1:1:1:1 to CHANTIX 1 mg BID, bupropion SR 150 mg BID, nicotine replacement therapy patch (NRT) 21 mg/day with taper or placebo for a treatment period of 12 weeks

Over the years, the composition of cigarettes has changed

Staley C, Weingarden AR, Khoruts A, Sadowsky MJ (2017) Interaction of gut microbiota with bile acid metabolism and its influence on disease states

Denvers Flavored Tobacco Ban Repeal Effort Outraises Opposition 2-to-1 The campaign to repeal Denvers ban on flavored tobacco products has raised nearly half a million dollars, with proponents out-fundraising the anti-tobacco side by more than a two-to-one margin