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Its noteworthy that previous studies extensively documented the pharmacological properties of durian fruit pulp extract, including its antiproliferative 30,31,32,33,34 , neuroprotective 35 , and antidiabetic 32 activities on human cell lines

First, since the donor substrate of O-GlcNAc modification, UDP-GlcNAc, is produced by the sequential integration of nutrients, including glucose, amino acids, fatty acids, and nucleotides, via HBP, O-GlcNAcylation is highly sensitive to the metabolic states of cells in living animals 2,3,12

Neuropeptides 27:1926, PMID: 7969817 Oja SS, Janky R, Varga V, Saransaari P (2000) Modulation of glutamate receptor functions by glutathione

Nevertheless, randomized double-blinded clinical trials will be required in order to objectively establish efficacy [343]